Abstract The microenvironment of immunosuppression and low immunogenicity of tumor cells has led to unsatisfactory therapeutic effects of the currently developed nanoplatforms.Immunogenic cell death, such as pyroptosis and ferroptosis, can efficiently boost antitumor immunity.However, the exploration of nanoplatform jackie square toe ariat slippers
Chronic pruritus is a major symptom of atopic dermatitis (AD).Its etiopathogenesis is complex, and an understanding of the driving factors of its pathogenesis allows for the development of new molecule-targeted therapies.Dupilumab, targeting and blocking interleukin-4 (IL-4) and interleukin-13 (IL-13) molecules, has shown great efficacy in treating
Oleaginous yeast Rhodosporidium toruloides has great biotechnological potential and scientific interest, yet the molecular rationale of its cellular behavior to carbon and nitrogen ratios with concurrent lipid agglomeration remains elusive.Here, metabolomics adaptations of the R.toruloides in response to varying glucose and nitrogen concentrations
Tropical cyclones (TCs) are highly destructive weather phenomena that cause extensive human and economic losses in affected regions.Accurate prediction of tropical cyclone intensity (TCI) is crucial for disaster preparedness and mitigation.Traditional TCI forecasting methods fail to extract nonlinear features and suffer from high computation costs.